Overview

SHARP for over 30 years has been at the forefront of the prevention of cardiovascular disease in Scotland. As we emerge from the effects of the COVID-19 pandemic our exciting educational programme continues with our November 2021 meeting.

Atrial fibrillation is a major risk factor for stroke. We will address both its detection and management, how to balance the benefit of prevention versus the risks and what is new in respect of national clinical guidance. The long term mortality and morbidity effects of coronary artery disease remains a major problem for society so it is both appropriate and important using a personalised approach, to examine recent therapeutic developments of heart failure in improving clinical outcomes.

We have become accustomised in the past two years to the benefits of technology enhanced consulting but wearable technology in the detection of heart disease continues to develop apace. Those attending the meeting will learn the role of technology in diagnosis and importantly what to do when faced with a printout from a patient using the latest ‘gizmo’.

We always need to look forward and more especially after a difficult two years. We are fortunate to have as a speaker, a worldwide expert of how the use of data will inform the management of patients with heart and vascular disease in the years ahead.

Finally, we are very proud of our continuing role in promoting the SHARP prize in the field of cardiovascular disease in order to showcase the work of young health professionals and helping to support and enhance their careers.

Please join us either in person or virtually for our 2021 hybrid meeting.

Programme
SLF Presentations
Causal AI: Personalizing Estimation of Cardiovascular Risk based on Cumulative Exposure to the Causes of Atherosclerosis

Professor Brian Ference
Director of Research (Professor) in Translational Therapeutics
Executive Director of the Centre for Naturally Randomized Trials, University of Cambridge

SHARP Meeting 2021 – Summary of Presentation (Professor Brian Ference)
Summary by Dr Michelle Collister-Bartlett, SHARP Trustee

The ASSIGN SCORE : here and now, and where next?

Professor Hugh Tunstall-Pedoe
Emeritus Professor and Senior Research Fellow, University of Dundee

SHARP Meeting 2021 – Summary of Presentation (Professor Hugh Tunstall-Pedoe)
Summary by Dr Michelle Collister-Bartlett, SHARP Trustee

Professor Mark Woodward, The George Institute for Global Health
Chair of Statistics, Epidemiology and Women’s Health, Imperial College of London
Professor of Medical Statistics, Faculty of Medicine, UNSW Sydney

Presentation: ASSIGN: where next?

Statinwise: a series of n-of-1 trials to assess muscle symptoms

Professor Liam Smeeth
Director of London School of Hygiene & Tropical Medicine

SHARP Meeting 2021 – Summary of Presentation (Professor Liam Smeeth)
Summary by Dr Michelle Collister-Bartlett, SHARP Trustee

Debate: Should Scotland adopt the 2019 ESC/EAS guidelines for lipid management?

Professor Chris Packard
Honorary Senior Research Fellow, Institute of CV & Medical Sciences, University of Glasgow

Dr Michael Murphy
Clinical Reader, School of Medicine, University of Dundee

SHARP Meeting 2021 – Summary of Presentation (Professor Chris Packard & Dr Michael Murphy)
Summary by Dr Michelle Collister-Bartlett, SHARP Trustee

siRNA based therapeutics for population health – the Inclisiran story

Professor Kosh Ray
Chair in Public Heath (Clinical), Department of Public Health & Primary Care, Imperial College London

SHARP Meeting 2021 – Summary of Presentation (Professor Kosh Ray)
Summary by Dr Michelle Collister-Bartlett, SHARP Trustee

SHARP Presentations
Opening Keynote Lecture: An Update on VTE for Cardiologists.

Dr Ander Cohen, Consultant Physician
Guy’s and St Thomas’ NHS Foundation Trust

Session sponsored by Bristol-Myers Squibb/Pfizer

SHARP Meeting 2021 – Summary of Presentation (Dr Ander Cohen)
Summary by Dr Michelle Collister-Bartlett, SHARP Trustee

Renal Outcome Trial Overview and Implementation – Product Specific presentation

Professor David Wheeler, Professor of Nephrology
University of College London

Session sponsored by AstraZeneca

SHARP Meeting 2021 – Summary of Presentation (Professor David Wheeler)
Summary by Dr Michelle Collister-Bartlett, SHARP Trustee

Community and individual detection of Atrial Fibrillation.  The tip of the iceberg?

Professor Lis Neubeck, Head of the Centre for Cardiovascular Health
School of Health and Social Care, Edinburgh Napier University

SHARP Meeting 2021 – Summary of Presentation (Professor Lis Neubeck)
Summary by Dr Michelle Collister-Bartlett, SHARP Trustee

The rise and rise of wearable technology, and what to do with it.

Dr Carmel McEniery, Senior Research Associate
University of Cambridge

SHARP Meeting 2021 – Summary of Presentation (Dr Carmel McEniery)
Summary by Dr Michelle Collister-Bartlett, SHARP Trustee

The 2021 SHARP Lecture

David on Goliath’s shoulders – how big data will inform healthcare.

Professor Calum MacRae, Executive Director, One Brave Idea
PI, Apple Heart & Movement Study
Vice Chair for Scientific Innovation, Department of Medicine, Brigham & Women’s Hospital
Professor of Medicine, Harvard Medical School
SHARP Prize 2021

The winners of the SHARP Prize 2021

Best SHARP Prize Poster (Non-Lipid Theme)
Ivy Ho, School of Medicine, University of Dundee, Dundee, UK
Prognostic Value of Clinical and Genomic Data on Predicting Major Adverse Cardiovascular Events (MACE)
Ho, Ivy – SHARP Prize 2021 Abstract Submission
Ho, Ivy – SHARP Prize 2021 Poster

Best SHARP Prize Poster (Lipid Theme)
Ruey Ping (Bernice) Teo, School of Medicine, University of Dundee, Dundee, UK
Audit of patient selection for Familial Hypercholesterolaemia (FH) genetic testing over a 2-year period with retrospective comparison of the Simon-Broome criteria vs the Dutch Lipid Clinic Network (DLCN) criteria vs the Wales FH service genotype scoring criteria.
Ruey Ping, Teo – SHARP Prize 2021 Abstract Submission
Ruey Ping, Teo – SHARP Prize 2021 Poster

Best SHARP Prize Presentation
Tilly Hamilton, Medical School, University of Edinburgh, UK & BHF Centre for Cardiovascular Science, University of Edinburgh, UK
Sex- and age-specific performance of the ASSIGN risk score for the prediction of cardiovascular events in the general population
Hamilton, Tilly – SHARP Prize 2021 Abstract Submission
Hamilton, Tilly – SHARP Prize 2021 Poster

Please take a moment to view the abstract submissions submitted for the 2021 SHARP Prize:

SHARP Prize Presenters

Sex- and age-specific performance of the ASSIGN risk score for the prediction of cardiovascular events in the general population
Tilly Hamilton, Medical School, University of Edinburgh, UK & BHF Centre for Cardiovascular Science, University of Edinburgh, UK
Hamilton, Tilly – SHARP Prize 2021 Abstract Submission
Hamilton, Tilly – SHARP Prize 2021 Poster

Improving Detection and Management of Atrial Fibrillation after Ischaemic Stroke in Glasgow (IMPROVE-AF): A Quality Improvement Project
Fiona Johnston, Medical School, University of Glasgow, Glasgow, UK
Johnston, Fiona – SHARP Prize 2021 Abstract Submission
Johnston, Fiona – SHARP Prize 2021 Poster

Pirfenidone improves insulin sensitivity & cardiac function in high-fat diet-induced obese and insulin-resistant mice
Vishal Musale, School of Medicine, University of Dundee, Dundee, UK
Musale, Vishal – SHARP Prize 2021 Abstract Submission
Musale, Vishal – SHARP Prize 2021 Poster

Magnesium Sulphate Treatment During Hypertensive Pregnancy Improves Maternal but not Fetal Outcomes in Rats
Kayley. Scott, Institute of Cardiovascular & Medical Sciences, University of Glasgow, Scotland, UK
Scott, Kayley – SHARP Prize 2021 Abstract Submission
Scott, Kayley – SHARP Prize 2021 Poster

SHARP Prize Posters

Relationship Between Cardiovascular Disease Pathology and Fatal Opioid and Other Sedative Overdose: A Post-Mortem Investigation and Pilot Study
Abdulmalik Zuhair Arab, School of Medicine, University of Dundee, UK
Arab, Malik – SHARP Prize 2021 Abstract Submission
Arab, Abdulmalik – SHARP Prize 2021 Poster

Determining the mechanism of myocardial injury and role of coronary disease in type 2 myocardial infarction: DEMAND-MI
Anda Bularga, Centre for Cardiovascular Science, University of Edinburgh, UK
Bularga, Anda – SHARP Prize 2021 Abstract Submission
Bularga, Anda – SHARP Prize 2021 Poster

Cumulative atherosclerotic burden in patients with angina and non-obstructive coronary artery disease (ANOCA).
Jaclyn Carberry, British Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK
Carberry, Jaclyn – SHARP Prize 2021 Abstract Submission
Carberry, Jaclyn – SHARP Prize 2021 Poster

Rapid Access Chest Pain Clinic at St. Johns Hospital.
Jacob Flapan, St. John’s Hospital, Livingstone, West Lothian, UK
Flapan, Jacob – SHARP Prize 2021 Abstract Submission
Flapan, Jacob – SHARP Prize 2021 Poster

Prognostic Value of Clinical and Genomic Data on Predicting Major Adverse Cardiovascular Events (MACE)
Ivy Ho, School of Medicine, University of Dundee, Dundee, UK
Ho, Ivy – SHARP Prize 2021 Abstract Submission
Ho, Ivy – SHARP Prize 2021 Poster

Investigating the Association Between Type 2 Diabetes and Parkinson’s Disease Using Electronic Medical Records in the GoDARTS Bioresource
Dana L. Hutton, School of Medicine, University of Dundee, Dundee, UK
Hutton, Dana – SHARP Prize 2021 Abstract Submission
Hutton, Dana – SHARP Prize 2021 Poster

Evaluating Best Medical Therapy Provision in Peripheral Arterial Disease Patients: A Prospective Audit
Peter Ishak, Vascular Surgery Department, University Hospital Ayr & Undergraduate Medical School, University of Glasgow, UK
Ishak, Peter – SHARP Prize 2021 Abstract Submission
Ishak, Peter – SHARP Prize 2021 Poster (2)

Evaluating clinical outcomes in temporal artery biopsy: a retrospective observational study
Peter Ishak, Vascular Surgery Department, University Hospital Ayr & Undergraduate Medical School, University of Glasgow, UK
Ishak Peter – SHARP Prize 2021 Abstract Submission
Ishak, Peter – SHARP Prize 2021 Poster

Antianginal Therapy Before Percutaneous Coronary Intervention in Stable Angina—a retrospective audit
Kashan Ali & Mya Win (Joint Authors), Department of Cardiology, Ninewells Hospital and Medical School, Dundee, UK
Ali, Kashan & Win, Mya – SHARP Prize 2021 Abstract Submission
Ali, Kashan & Win, Mya – SHARP Prize 2021 Poster

Association of lipoprotein(a) with CT coronary calcium score in a multi-ethnic, asymptomatic cohort of patients referred to a tertiary lipid clinic
Benjamin Low, Department of Cardiology, Imperial College Healthcare NHS Trust, London, UK
Low, Benjamin – SHARP Prize 2021 Abstract Submission
Low, Benjamin – SHARP Prize 2021 Poster

Finding Familial Hypercholesterolaemia After The Event
Calvin MacKinnon, Aberdeen Royal Infirmary, Aberdeen, UK
MacKinnon, Calvin – SHARP Prize 2021 Abstract Submission
MacKinnon, Calvin – SHARP Prize 2021 Poster

Understanding How Educational Interventions Improve Treatment Adherence In Patients With Familial Hypercholesterolaemia:  A Systematic Review
Hannah Massey, Scottish Clinical Genetics Services in Aberdeen, UK
Massey, Hannah – SHARP Prize 2021 Abstract Submission
Massey, Hannah – SHARP Prize 2021 Poster

The routine clinical use of FIB-4 in lipid clinics
Ruvini NK Ranasinghe, Department of Clinical Biochemistry, King’s College Hospital, NHS Foundation Trust, London, UK
Ranasinghe, Ruvini – SHARP Prize 2021 Abstract Submission
Ranasinghe, Ruvini – SHARP Prize 2021 Poster

Audit of patient selection for Familial Hypercholesterolaemia (FH) genetic testing over a 2-year period with retrospective comparison of the Simon-Broome criteria vs the Dutch Lipid Clinic Network (DLCN) criteria vs the Wales FH service genotype scoring criteria.
Ruey Ping (Bernice) Teo, School of Medicine, University of Dundee, Dundee, UK
Ruey Ping, Teo – SHARP Prize 2021 Abstract Submission
Ruey Ping, Teo – SHARP Prize 2021 Poster

Audit of PCSK-9 Inhibitor Prescribing in GGC: Real Patient Data
Rufus Turner, Beatson West of Scotland Cancer Centre, UK
Turner, Rufus – SHARP Prize 2021 Abstract Submission
Turner, Rufus – SHARP Prize 2021 Poster

Differences in clinical characteristics, management and outcomes between men and women with type 2 myocardial infarction stratified by mechanism of injury
Emma Watkinson, University of Edinburgh, UK
Watkinson, Emma – SHARP Prize 2021 Abstract Submission
Watkinson, Emma – SHARP Prize 2021 Poster

A retrospective comparison of the Simon Broome and Dutch Lipid Clinic Network criteria for the diagnosis of Familial Hypercholesterolaemia in the Glasgow Clyde sector
Kirsten Grant, Glasgow Royal Infirmary, UK
Grant, Kirsten – SHARP Prize 2021 Abstract Submission

Genetic Testing for Hypertriglyceridaemia in the UK
Georgios Kounidas, University of Aberdeen, UK
Kounidas, Georgios – SHARP Prize 2021 Abstract Submission
Kounidas, Georgios – SHARP Prize 2021 Poster

Opportunities for Primary Prevention of Cardiovascular Disease observed through Incidental Findings of Elevated Lipid Profiles in Clinical Research Centre Trial Participants
Mon M Oo & Christine Almaden-Boyle, University of Dundee, UK
Oo, Mon & Almaden-Boyle, Christine – SHARP Prize 2021 Abstract Submission
Oo, Mon & Almaden-Boyle, Christine – SHARP Prize 2021 Poster

Troponin in the chronic coronary syndrome
Ryan Wereski, BHF/University Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK
Wereski, Ryan – SHARP Prize 2021 Abstract Submission
Wereski, Ryan – SHARP Prize 2021 Poster

Sponsors

                               

This event was funded by the above companies through event sponsorship and sponsored sessions for which we are very grateful.  These companies had no input into the design or content of the agenda (other than their own sessions) but were in attendance on the day.

The Bristol-Myers Squibb/Pfizer Alliance funded and organised the sponsored lunchtime session on the agenda.

Recording of Meeting

You can watch the SLF & SHARP Hybrid Meeting 2021 by clicking on the link below:

Address – https://vimeo.com/showcase/9073010

Password – lpsh21UM

Venue & Covid-19 Risk Assessment & Information

We offered delegates the option to attend virtually or in person at the Royal College of Physicians of Edinburgh.

Set in the heart of Edinburgh’s city centre, the College offers both historic elegance and state of the art venue facilities. With stunning architecture and medical symbolism weaved throughout, it was the perfect venue to host our annual meeting.

RCPE who prepared as part of their Risk Communications Strategy a comprehensive COVID -19 information and good guidance leaflet for those attending the college in person. This guidance was provided to all attendees and can be viewed below:

RCPE Risk Assessment

Covid-19 Information for Attendees

Testimonials from SLF & SHARP Hybrid Meeting 2021

‘High standard educational event’

Sponsor Testimonial

‘Hybrid format and venue – a welcome departure from virtual world’

Sponsor Testimonial

‘Delighted to sponsor the event – will gladly do so in coming years’

Sponsor Testimonial

‘RCPE worked well – central special venue’

Sponsor Testimonial

‘Beautiful venue’

Sponsor Testimonial

‘Format worked well’

Sponsor Testimonial

‘Such an interesting event – pleasure to sponsor’

Sponsor Testimonial